Tae Takemi, the enigmatic and slightly morbid doctor of Yongen-Jaya, is one of the most rewarding confidants to max out in Persona 5 Royal. Beyond her intriguing personality and storyline, Takemi’s confidant abilities offer invaluable in-game benefits, making her “clinical trials” a must-do for any Phantom Thief. This Takemi Confidant Guide will walk you through every step to strengthen your bond with the Death Arcana doctor, unlocking powerful perks and maybe even a romance along the way.
Unlocking Takemi: Availability and Requirements
Takemi’s Availability
You can begin your journey with Doctor Takemi as early as 4/18. Her clinic, nestled in Yongen-Jaya, just around the corner from Leblanc, becomes your go-to destination. Takemi is generally available after school most days, allowing you to easily fit in visits between your other Phantom Thief activities.
However, progress with Takemi isn’t just about showing up. You’ll need to prove your mettle. To advance beyond the initial meeting and reach Rank 2, you’ll need Rank 2 Guts. Later on, at Rank 7.5, another hurdle appears, requiring Rank 4 Charm to continue deepening your bond. Don’t worry about the Guts requirement too much initially, as participating in Takemi’s clinical trials themselves will reward you with +1 Guts each time, naturally helping you meet the requirement.
For those seeking a deeper connection, romancing Takemi unlocks a special perk: she becomes available at night once your relationship blossoms, offering more flexible hangout times.
Takemi’s Confidant Perks: Your Clinic Arsenal
Takemi’s confidant perks are undeniably some of the most useful in Persona 5 Royal. As you deepen your bond, her clinic transforms into a treasure trove of healing and support items. These items are crucial for surviving the demanding palaces and Mementos, and Takemi’s perks make them increasingly accessible and affordable.
| Rank | Ability | Description |
|---|---|---|
| 1 | Rejuvenation | Expands the selection of healing items available at Takemi’s clinic. |
| 3 | Sterilization | Further increases the variety of healing items stocked at the clinic. |
| 5 | Immunization | Introduces valuable support items to Takemi’s clinic inventory. |
| 7 | Discounted | Slashes the price of all items sold at Takemi’s clinic by an incredible 50%! |
| 10 (Max) | Resuscitation | Augments the clinic’s stock with powerful revival items. |
With these perks, a visit to Takemi’s clinic becomes essential before any major palace infiltration. Stocking up on discounted, high-quality healing and support items will significantly increase your survivability and efficiency in combat.
Ranking Up Takemi’s Confidant: A Step-by-Step Guide
Like other confidants in Persona 5 Royal, ranking up your relationship with Takemi is achieved by spending quality time with her. For Takemi, this primarily involves participating in her clinical trials.
Remember, Takemi is the Death confidant. To maximize the affinity points you earn during each interaction, always bring a Persona of the Death arcana with you when you visit her clinic. This simple step will ensure you rank up faster and more efficiently.
Takemi’s Persona 5 Royal Confidant, Rank 1
Completing this initial scene will reward you with +1 Guts.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “… What exactly are you up to?” | “It’s for brainpower.” | – | – |
| “It’s for my exams.” | – | – | |
| “It’s for studying.” | – | – | |
| “Why don’t you have an energy drink or something?” | “I need that medicine.” | – | – |
| “I’ll tell people.” | – | – | |
| “So how about you just go home?” | “I’m not leaving.” | – | – |
| “Can I work for it?” | – | – | |
| “… Are you up for it?” | “What would I be doing?” | – | – |
| “How much does it pay?” | – | – | |
| “Well? Go on.” | “Don’t mind if I do.” | – | – |
| “Bottoms up.” | – | – | |
| “Are you out of your mind? Only an idiot would have drank that.” | “I’m not outta my mind.” | – | – |
| “It’s for my exams.” | – | – | |
| “So you’re strictly prohibited from disclosing what happens here to anyone… Understood?” | “Of course.” | – | – |
| “Same goes for you.” | – | – | |
| “Based on today’s results, I think I can whip up some new medicine for next time. Drop by when you’re ready for it.” | “Fine by me.” | 2 | 1 |
| “Please go easy on me.” | 3 | 3 | |
| “So many pretty lights…” | 2 | 1 |
Takemi’s Persona 5 Royal Confidant, Rank 2
Reaching this rank requires Rank 2 Guts. You’ll also earn +1 Guts after this scene.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| (Arrogant Officer) “You don’t seem to be sick… Are you up to something illegal!?” | “I have a bad heart.” | 2 | 1 |
| “We’re on a date.” | – | – | |
| “I know my rights.” | – | – | |
| “*sigh* I’m so over this…” | “I agree.” | 2 | 1 |
| “Harassment?” | – | – | |
| “The Plague?” | – | – | |
| “You know how it is. Some patients get sick on their way back home.” | “I’m totally fine.” | 2 | 1 |
| “I feel lightheaded.” | – | – | |
| “I think I have superpowers.” | 2 | 1 |
Takemi’s Persona 5 Royal Confidant, Rank 3
You’ll earn +1 Guts after this scene.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “… Awfully rude, just hanging up on a lady like that.” | “What was that about?” | – | – |
| “Was that an emergency?” | – | – | |
| “They call me the Plague… due to a grave medical error I made.” | “A medical error?” | – | – |
| “What do you mean?” | – | – | |
| “Participating in clinical trials run by a doctor like that?” | “I don’t mind.” | 2 | 1 |
| “Is it true?” | – | – | |
| “I need the medicine.” | 2 | 1 | |
| “You… haven’t told anyone about my drugs, right?” | “Of course not.” | 2 | 1 |
| “I don’t think I did…” | – | – | |
| “Have you?” | – | – |
Takemi’s Persona 5 Royal Confidant, Rank 4
You’ll earn +1 Guts after this scene.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “……” | “You’ll be OK.” | – | – |
| “Dr. Takemi will help.” | 2 | 1 | |
| “… Hehe.” | “You seem happy.” | 3 | 2 |
| “You’re so kind.” | 2 | 1 | |
| “Why free?” | 2 | 1 | |
| “Especially after approving that girl’s consultation without my permission.” | “I’ll reflect on my mistakes.” | 2 | 1 |
| “But she ended up okay.” | – | – | |
| “Punish me more.” | – | – |
Takemi’s Persona 5 Royal Confidant, Rank 5
You’ll earn +1 Guts after this scene.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “I even told them about the medical error I made…” | “They trust you.” | – | – |
| “Was it really your fault?” | – | – | |
| “… No matter what I said, I couldn’t change how they felt about me.” | “I had no idea.” | – | – |
| “It’s not too late.” | – | – | |
| “That’s why it’s harmless for people who don’t have the disease… probably.” | “That’s good.” | 3 | 2 |
| “When will it be done?” | 2 | 1 | |
| “… ‘Probably?'” | – | – | |
| “Also… sorry for the long talk today. I wasn’t planning on telling you all that.” | “About Miwa-chan?” | 2 | 1 |
| “About Oyamada?” | – | – | |
| “About Crawford-Ende’s?” | – | – |
Takemi’s Persona 5 Royal Confidant, Rank 6
You’ll earn +1 Guts after this scene.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “*sigh* … What the heck?” | “Well, someone’s popular.” | – | – |
| “You seem annoyed.” | – | – | |
| “Did something happen?” | – | – | |
| “Sheesh. It’s not like I’m some kind of genius doctor.” | “Having fun?” | – | – |
| “You ARE a genius.” | – | – | |
| “That’s my role as the Plague. I’m not suited for all this other stuff.” | “You’re a masochist.” | – | – |
| “It suits you.” | 3 | 2 | |
| “You’re not honest.” | 2 | 2 | |
| “I’ll need you to stick around just a little bit longer. I hope you can handle it.” | “You can count on me.” | 2 | 1 |
| “I think I’m at my limit…” | – | – | |
| “Anything for you.” | 2 | 1 |
Takemi’s Persona 5 Royal Confidant, Rank 7
You’ll earn +1 Guts after this scene.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “……” | “This is harassment.” | 2 | 1 |
| “She’s a great doctor.” | 2 | 1 | |
| “Please be quiet.” | 2 | 1 | |
| “There’s no way…” | “Don’t lose hope.” | – | – |
| “Let’s ask for details.” | – | – | |
| “……” | – | – | |
| “I can’t…” | “Just rest for today.” | 2 | 1 |
| “Anything I can do?” | 2 | 1 | |
| “Let’s retaliate.” | – | – | |
| “Ugh. I wish I hadn’t shown you that side of me…” | “It was inevitable.” | – | – |
| “We all do sometimes.” | 3 | 2 | |
| “I’m glad you did.” (First romance flag) | 2 | 1 |
Takemi’s Persona 5 Royal Confidant, Rank 7.5
To progress beyond this point, you must have reached Rank 4 Charm.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “They’re probably being pressured by Oyamada to stop doing business with me. So I figure it’s over.” | “What about Miwa-chan?” | – | – |
| “You OK with this?” | – | – | |
| “I’m all out of allies…” | “Don’t give up.” | – | – |
| “Anything you can do?” | – | – | |
| “I’m your ally.” (Second romance flag) | 2 | 1 | |
| “So… thank you.” | “You gonna run away?” | – | – |
| “And your patients?” | – | – | |
| “Bye…” | “What’s his full name?” | – | – |
| “Tell me about him.” | – | – | |
| “You mean Oyamada? Why? I hope you’re not planning to get revenge for me.” | “I won’t do anything.” | – | – |
| “It’s for my research.” | – | – |
Takemi’s Persona 5 Royal Confidant, Rank 8
Before starting this rank, you must complete the “Bad Medicine” Mementos request. You will earn +1 Guts after completing this scene.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “It doesn’t change the fact that I couldn’t save her…” | “Miwa-chan is alive.” | – | – |
| “Oyamada lied to you.” | – | – | |
| “So she’s… she’s alive…” | “You should hurry.” | 2 | 1 |
| “Let’s get to work, doctor.” | 3 | 3 | |
| “It’s not over yet.” | 3 | 2 | |
| “… Sorry. Just hang in there, OK?” | “It’s for Miwa-chan.” (Third romance flag) | 3 | 3 |
| “It’s for my exams.” | 2 | 1 | |
| “It’s for you.” | 3 | 2 | |
| “Miwa-chan was fighting all that time. I have to fight for her, too.” | “I’ll be cheering you on.” | 2 | 1 |
| “Don’t burn yourself out.” | – | – | |
| “Anything else I can do?” | 2 | 1 |
Takemi’s Persona 5 Royal Confidant, Rank 9
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “I have to thank you again. All this is thanks to you helping me with the clinical trials.” | “Don’t worry about it.” | 2 | 1 |
| “It was for my exams.” | 2 | 1 | |
| “It was rough.” | 3 | 2 | |
| “I start first thing next month. Unfortunately, Takemi Clinic of Internal Medicine will be gone.” | “That’s troubling.” | – | – |
| “And your patients?” | – | – | |
| “Why don’t you tell me the truth about why you kept coming to me?” | “I wanted to see you.” | Final romance flag, proceeds to the next prompt | |
| “It was for my exams.” | *Friendship path confirmed**, ends the conversation* | ||
| “… Don’t tell me you’re in love with me or something.” | “I love you.” | 2 | 1 |
| “What do you think?” | *Friendship path confirmed**, ends the conversation* | ||
| “Or… I can give you a ‘special examination’ if you’d like.” | “It isn’t a joke.” | 3 | 3 |
| Romance path confirmed after receiving these affinity points, proceeds to the next prompt | |||
| “That sounds good.” | *Friendship path confirmed**, ends the conversation* | ||
| “Turns out my little guinea pig caught an illness that’s even more annoying and persistent than Crawford-Ende’s.” | “It’s true love.” | – | – |
| “So did you.” | 2 | 1 | |
| “I’ve always loved you.” | – | – | |
| “You really are the best guinea pig I could’ve hoped for.” | “You’re welcome.” | – | – |
| “It was a breeze.” | – | – | |
| “I’m glad we saw it through.” | 2 | 1 |
Takemi’s Persona 5 Royal Confidant, Rank 10 (Friendship)
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “… For your escapades with the Phantom Thieves, I mean.” | “Uh, what?” | – | – |
| “Is that a joke?” | – | – | |
| “And to have it happen when it did… Isn’t the only logical conclusion to think that it’s you?” | “It’s a coincidence.” | – | – |
| “I wonder…” | 2 | 1 | |
| “So what if it’s true?” | – | – |
Takemi’s Persona 5 Royal Confidant, Rank 10 (Romance)
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| “… For your escapades with the Phantom Thieves, I mean.” | “Uh, what?” | – | – |
| “Is that a joke?” | – | – | |
| “And to have it happen when it did… Isn’t the only logical conclusion to think that it’s you?” | “It’s a coincidence.” | – | – |
| “I wonder…” | 2 | 1 | |
| “So what if it’s true?” | – | – | |
| “Really… Then, would you like a ‘thorough examination’?” | “What kind?” | 2 | 1 |
| “Yes, please.” | 3 | 2 |
Upon reaching Rank 10, Takemi’s clinic will have its full inventory unlocked. Make sure to regularly check her stock for the best healing, support, and revival items in Persona 5 Royal.
Non-Ranking Scenes From Takemi’s Confidant
Beyond the structured rank-up events, Persona 5 Royal offers opportunities to spend time with Takemi in non-ranking scenes. These hangouts are excellent for earning bonus affinity points, bringing you closer to the next confidant rank and further solidifying your bond.
| Dialogue | Your Response | Points Earned With A Matching Persona | Points Earned Without A Matching Persona |
|---|---|---|---|
| Inokashira Park (Unavailable on rainy days) (Only available between Ranks 3-9) | |||
| “Well then, shall we begin?” | “You’re changing something?” | 3 | 2 |
| “What’re you gonna make me do?” | 3 | 2 | |
| “What’s on today’s menu?” | 3 | 3 | |
| Asakusa (Sky Tree Tower) (Unavailable on rainy days) (Only available between Ranks 6-9) | |||
| “The atmospheric pressure should have dropped at this height. Are your ears okay?” | “They feel weird.” | 3 | 2 |
| “My heart is pounding.” | 3 | 3 | |
| “I’m completely fine.” | 3 | 2 | |
| Odaiba Ferris Wheel (Exclusive to the romantic path) | |||
| “You take your medicine without batting an eye. I wonder if I can break those nerves of steel.” | “I just put up with it.” | 3 | 2 |
| “That’s my line.” | 3 | 2 | |
| “Try all you want.” | 3 | 3 | |
| Leblanc Attic (Exclusive to the romantic path) | |||
| “You’ve been living here for a while now. How do you like it?” | “It’s a great place.” | 3 | 2 |
| “It’s got its charm.” | 3 | 2 | |
| “It’s better when you’re here.” | 3 | 3 |
Even if you choose a different romantic path, these non-ranking scenes offer valuable opportunities to deepen your friendship with Takemi and unlock her full potential as a confidant.
